Peer-reviewed veterinary case report
Fosfomycin works against E. coli in dogs with pyometra
By Inoue, Ikuo et al.·Published in The Journal of veterinary medical science·2013·The United Graduate School of Veterinary Sciences, Japan·View original on PubMed →
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Original publication title: Efficacy of fosfomycin on Escherichia coli isolated from bitches with pyometra.
Plain-English summary
A group of female dogs with a serious uterine infection called pyometra was found to have E. coli bacteria that were resistant to several common antibiotics. Researchers tested various antibiotics and found that fosfomycin was the only one that remained effective against these bacteria. Since many of the E. coli strains were resistant to multiple drugs, using fosfomycin could be a good treatment option for these dogs. This suggests that if your dog has pyometra and is showing signs of infection, fosfomycin might be a safe choice for treatment.
People also search for: dog pyometra treatment · E. coli infection in dogs · antibiotic resistance in dogs
Abstract
The aim of this study was to determine the antimicrobial resistance of Escherichia coli isolated from the uteri of bitches with pyometra, and 38 E. coli isolates were used. The antimicrobials used were ampicillin (ABPC), amoxicillin/clavulanic acid, gentamicin, minocycline, cefazolin, levofloxacin (LVFX), trimethoprim-sulfamethoxazole (ST) and fosfomycin (FOM). Resistance to ABPC occurred most frequently, followed by LVFX and ST. Multi-drug resistance, defined as resistance against 3 or more classes of antimicrobials, was found in 23.7% of all isolates. Nine out of 13 resistant strains were multi-drug resistant, but no strain was found to be resistant to FOM. This suggests that FOM should be administered for E. coli from pyometra.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23257546/