Peer-reviewed veterinary case report
Hyposensitization treatment helps cats with allergies based
By Halliwell, R E·Published in Journal of the American Animal Hospital Association·1997·Department of Veterinary Clinical Studies, United Kingdom·View original on PubMed →
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Original publication title: Efficacy of hyposensitization in feline allergic diseases based upon results of in vitro testing for allergen-specific immunoglobulin E.
- Species:
- cat
Plain-English summary
A group of cats with allergic diseases were treated with hyposensitization therapy, which helps their immune system respond better to allergens. Out of 81 cats, many showed improvement, especially those with skin issues like linear granuloma and allergic asthma. In fact, over 75% of the cats had at least a 50% improvement when they combined this therapy with dietary changes. However, some cats did not respond well to the treatment and had to stop. Overall, this approach seems promising for managing allergies in cats.
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Abstract
A survey was undertaken to evaluate the responses to hyposensitization in cats for which a diagnosis of allergic disease was made by assessment of clinical signs and evaluation of allergen-specific immunoglobulin E (IgE) using the radioallergosorbent test (RAST). Eighty-one cases were available for analysis. In 39 cases, a dietary change resulted in some subjective improvement, which usually was minimal; however, some cases had significant improvement. In 75.3% of cases, an improvement of at least 50% was noted and ascribed to a combination of immunotherapy and dietary change, when implemented. The response of the 42 cases in which immunotherapy alone was used or where there was no response to dietary change was broadly similar. Response of the specific dermatological conditions ranged from 93.6% in the case of linear granuloma to 60% in cases where self-induced hair loss was evident. Response also was good in cases of presumed allergic asthma (86.1% improvement) and suspected allergic otitis externa (62.6% improvement). In nine patients, the hyposensitization was discontinued due to lack of response. The results suggest that confirmation of a suspected diagnosis of allergic disease in cats by means of in vitro tests and subsequent therapy with hyposensitization should be a major consideration in feline practice.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9138241/