Peer-reviewed veterinary case report
Iopanoic acid treatment for hyperthyroidism in cats
By Gallagher, Alexander E. & Panciera, David L.·Published in Journal of Feline Medicine and Surgery·2011·Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA, United States·View original on Crossref →
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Original publication title: Efficacy of iopanoic acid for treatment of spontaneous hyperthyroidism in cats
- Species:
- cat
Plain-English summary
An 11-year-old domestic shorthair cat was diagnosed with hyperthyroidism, which can cause symptoms like increased thirst, weight loss, and hyperactivity. The cat was treated with iopanoic acid, a medication typically used in humans, to see if it could help manage the condition. While some improvement was noted in the first few weeks, the benefits were short-lived, and there were no significant long-term improvements in the cat's health. This suggests that while iopanoic acid might help temporarily, it isn't a good option for ongoing treatment of hyperthyroidism in cats.
People also search for: cat hyperthyroidism treatment · iopanoic acid for cats · symptoms of cat hyperthyroidism
Abstract
Iopanoic acid is an iodine containing oral cholecystographic agent that has been used to treat hyperthyroidism in humans and has recently been evaluated in an experimental model of feline hyperthyroidism. The aim of this study was to evaluate the efficacy of iopanoic acid in cats with spontaneous hyperthyroidism. Eleven cats were included in the study. Eight were treated initially with 50 mg orally q 12 h and three were treated with 100 mg orally q 12 h. Prior to treatment (baseline) and at 2, 4, and 12 weeks of treatment, owner questionnaires, physical exams, complete blood count, biochemistry analyses, and T 3 and T 4 concentrations were evaluated. The mean serum T 3 concentration decreased with treatment at all time periods compared to baseline. Mean T 4 concentrations were increased at weeks 4 and 12 compared to baseline. Five cats had a partial response during the initial 4 weeks of therapy, but the effects were transient and no significant improvements in clinical signs or physical exam findings were noted at any time period. Results suggest that iopanoic acid may be beneficial for acute management of thyrotoxicosis in some cats, but is not suitable for long-term management.
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Search related cases →Original publication on Crossref: https://doi.org/10.1016/j.jfms.2011.02.003