Peer-reviewed veterinary case report
Iopanoic acid treatment lowers thyroid hormone in cats
By Gallagher, Alexander E & Panciera, David L·Published in Journal of feline medicine and surgery·2011·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Efficacy of iopanoic acid for treatment of spontaneous hyperthyroidism in cats.
- Species:
- cat
Plain-English summary
A group of 11 cats with hyperthyroidism (an overactive thyroid) were treated with iopanoic acid, a medication usually used in humans. The cats received either 50mg or 100mg of the medication twice a day. While some cats showed a temporary decrease in thyroid hormone levels during the first month, overall, there were no significant improvements in their symptoms or health after 12 weeks. This suggests that while iopanoic acid might help in the short term, it isn't effective for long-term treatment of hyperthyroidism in cats.
People also search for: cat hyperthyroidism treatment · iopanoic acid for cats · symptoms of cat thyroid problems
Abstract
Iopanoic acid is an iodine containing oral cholecystographic agent that has been used to treat hyperthyroidism in humans and has recently been evaluated in an experimental model of feline hyperthyroidism. The aim of this study was to evaluate the efficacy of iopanoic acid in cats with spontaneous hyperthyroidism. Eleven cats were included in the study. Eight were treated initially with 50mg orally q 12h and three were treated with 100mg orally q 12h. Prior to treatment (baseline) and at 2, 4, and 12 weeks of treatment, owner questionnaires, physical exams, complete blood count, biochemistry analyses, and T(3) and T(4) concentrations were evaluated. The mean serum T(3) concentration decreased with treatment at all time periods compared to baseline. Mean T(4) concentrations were increased at weeks 4 and 12 compared to baseline. Five cats had a partial response during the initial 4 weeks of therapy, but the effects were transient and no significant improvements in clinical signs or physical exam findings were noted at any time period. Results suggest that iopanoic acid may be beneficial for acute management of thyrotoxicosis in some cats, but is not suitable for long-term management.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21515081/