Peer-reviewed veterinary case report
Manuka honey combined with antifungals for dog and cat yeast
By Váczi, P et al.·Published in Polish journal of veterinary sciences·2023·Department of Pharmacology and Toxicology·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Efficacy of manuka honey with conventional antifungals on.
- Species:
- dog
Plain-English summary
A group of dogs with yeast infections, which can cause skin issues like itchy ears and flaky skin, were treated with a combination of manuka honey and standard antifungal medications. The study found that using manuka honey alongside antifungals like clotrimazole and fluconazole made the treatments more effective than using either alone. This suggests that manuka honey could be a helpful addition to traditional treatments for yeast infections in dogs.
People also search for: dog yeast infection treatment · manuka honey for dog skin problems · antifungal medication for dogs
Abstract
Yeast infections such as otitis externa and seborrheic dermatitis in dogs and cats are frequently associated withsecondary infection. It is part of the normal cutaneous microflora of most warm-blooded vertebrates, however, under certain conditions, it can become a causative agent of infection that needs to be treated pharmacologically. Azole derivatives are the drugs of the first choice. An interesting trend in developing resistance is the use of natural substances, which include manuka honey with confirmed antimicrobial properties. The main intention of this research was to evaluate the mutual effect of manuka honey in combination with four conventional azole antifungals - clotrimazole, fluconazole, itraconazole, and miconazole - on 14isolates obtained from dogs and 1 reference strain. A slightly modified M27-A3 method (CLSI 2008) and the checkerboard test (Nikolić et al. 2017) were used for this purpose. Our results show an additive effect of all 4 antifungals with manuka honey concurrent use. Based on the determined values of fractional inhibitory concentration index (FICI - 0.74±0.03 when manuka honey combined with clotrimazole, 0.96±0.08 with fluconazole, 1.0±0 with miconazole and 1.16±0.26 with itraconazole), it was found in all cases that the effect of substances used is more pronounced in mutual combination than when used separately.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37389413/