Peer-reviewed veterinary case report
Maropitant stops vomiting from car sickness in dogs
By Benchaoui, H A et al.·Published in The Veterinary record·2007·Pfizer Animal Health·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Efficacy of maropitant for preventing vomiting associated with motion sickness in dogs.
- Species:
- dog
Plain-English summary
A group of dogs with a history of motion sickness were given either a medication called maropitant or a placebo before car rides to see if it would help prevent vomiting. In one study, 10 out of 17 dogs on the placebo vomited during the trip, while only 3 dogs given maropitant did. In a larger study, 69 out of 105 dogs on the placebo vomited, compared to just 15 out of 106 dogs treated with maropitant. This shows that maropitant is effective in reducing vomiting in dogs during car travel.
People also search for: dog car sickness treatment · maropitant for dog vomiting · how to stop dog from vomiting in car
Abstract
Maropitant is a neurokinin-1 inhibitor that acts to prevent and treat vomiting by blocking stimuli to the final common pathway in the emetic centre of the brain. The field efficacy and safety of a single oral dose of maropitant were investigated for the prevention of vomiting in dogs with a history of motion sickness resulting from transportation by car in two blinded, placebo-controlled studies. In an exploratory study designed as a two-way crossover trial with 17 dogs, 10 of the dogs given the placebo vomited during a car journey but only three of the dogs vomited under maropitant treatment. In a larger multicentred parallel design study, 69 of 105 dogs treated with the placebo vomited during the journey compared with 15 of 106 dogs treated with maropitant (P < 0.0001).
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17906225/