Peer-reviewed veterinary case report
Maropitant stops vomiting in dogs given hydromorphone before surgery
By Hay Kraus, Bonnie L·Published in Veterinary anaesthesia and analgesia·2013·Department of Clinical Sciences, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Efficacy of maropitant in preventing vomiting in dogs premedicated with hydromorphone.
- Species:
- dog
Plain-English summary
Eighteen dogs scheduled for orthopedic surgery were given either maropitant (Cerenia) or a saline solution before receiving hydromorphone, a common pain medication. The dogs that received the saline experienced vomiting, retching, or signs of nausea, while none of the dogs that received maropitant showed these symptoms. This study found that maropitant is effective in preventing vomiting and nausea after hydromorphone administration in dogs. If your dog needs surgery and you're concerned about vomiting, ask your vet about using maropitant.
People also search for: dog vomiting after surgery · maropitant for dogs · hydromorphone side effects in dogs
Abstract
OBJECTIVE: The goal of this study was to evaluate the effectiveness of maropitant (Cerenia(®)) in preventing vomiting after premedication with hydromorphone. STUDY DESIGN: Randomized, blinded, prospective clinical study. ANIMALS: Eighteen dogs ASA I/II admitted for elective orthopedic surgical procedures. The dogs were a mixed population of males and females, purebreds and mixed breeds, 1.0-10.2 years of age, weighing 3-49.5 kg. METHODS: Dogs were admitted to the study if they were greater than 1 year of age, healthy and scheduled to undergo elective orthopedic surgery. Dogs were randomly selected to receive one of two treatments administered by subcutaneous injection. Group M received 1.0 mg kg(-1) of maropitant, Group S received 0.1 mL kg(-1) of saline 1 hour prior to anesthesia premedication. Dogs were premedicated with 0.1 mg kg(-1) of hydromorphone intramuscularly. A blinded observer documented the presence of vomiting, retching and/or signs of nausea for 30 minutes after premedication. RESULTS: All dogs in S vomited (6/9), retched (1/9) or displayed signs of nausea (2/9). None (0/9) of the dogs in M vomited, retched or displayed signs of nausea. Dogs in M had significantly fewer incidences of vomiting (p=0.0090), vomiting and retching (p=0.0023) and vomiting, retching and nausea (p<0.0001) when compared to S. CONCLUSION AND CLINICAL RELEVANCE: Maropitant prevents vomiting, retching and nausea associated with intramuscular hydromorphone administration in dogs.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23082784/