Peer-reviewed veterinary case report
Milbemycin oxime kills hookworm larvae and adults in cats
By Humbert-Droz, E et al.·Published in The Veterinary record·2004·Novartis Centre de Recherche Santé·View original on PubMed →
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Original publication title: Efficacy of milbemycin oxime against fourth-stage larvae and adults of Ancylostoma tubaeforme in experimentally infected cats.
- Species:
- cat
Plain-English summary
A group of young domestic shorthair cats was intentionally infected with hookworm larvae and then treated with a medication called milbemycin oxime to see how well it worked against the worms. After treatment, the cats showed a significant reduction in both the number of worm eggs in their feces and the actual worms in their bodies, with reductions of over 99% for the eggs and up to 99.2% for adult worms. This suggests that milbemycin oxime is highly effective for treating hookworm infections in cats.
People also search for: cat hookworm treatment · milbemycin for cats · how to get rid of worms in cats
Abstract
The efficacy of milbemycin oxime against fourth-stage (L4) larvae and adults of Ancylostoma tubaeforme was investigated in a trial involving 24 young domestic shorthair cats. The animals were inoculated with approximately 300 infective stage three (L3) larvae and divided into three groups. After 12 days, eight cats (group 1) were treated with medicated tablets containing 4 mg milbemycin and 10 mg praziquantel to test the efficacy against L4 larvae; eight cats in group 2 were treated with the same tablets after 33 days to test the efficacy against adult worms; and eight cats in group 3 were treated with a placebo tablet. Faecal egg counts were determined periodically in each cat and after 40 or 41 days the number of worms in each animal was determined postmortem. The egg count reduction was determined by comparing the geometric mean numbers of eggs per gram of faeces in the placebo and medicated groups, and the worm reduction by comparing the geometric mean numbers of worms. The egg count reduction was more than 99 per cent in both treated groups, while the number of worms in groups 1 and 2 were reduced by 94.7 per cent and 99.2 per cent, respectively.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14979442/