Peer-reviewed veterinary case report
Phototherapy with 308-nm light improves skin in dogs with atopic
By Park, Ju-Yong et al.·Published in Frontiers in Veterinary Science·2021·View original on Crossref →
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Original publication title: Efficacy of Phototherapy With 308-nm Excimer Light for Skin Microbiome Dysbiosis and Skin Barrier Dysfunction in Canine Atopic Dermatitis
- Species:
- dog
Plain-English summary
A group of dogs with atopic dermatitis (an allergic skin condition) received phototherapy using a special 308-nm excimer light once a week for two months. This treatment helped improve their skin health by changing the skin's microbiome and reducing symptoms like itching and inflammation. After the therapy, the dogs showed better skin barrier function and less water loss, indicating healthier skin. Overall, the excimer light therapy was effective and safe for treating canine atopic dermatitis.
People also search for: dog skin allergies treatment · excimer light therapy for dogs · atopic dermatitis in dogs symptoms
Abstract
The management of canine atopic dermatitis, an allergic skin disorder, is challenging. To investigate the effect of phototherapy using a 308-nm excimer light as a topical treatment for canine atopic dermatitis, 10 dogs with canine atopic dermatitis and 10 with non-allergic skin were enrolled in this study. Phototherapy was applied every 7 days for a total of 2 months. The skin microbiome, skin barrier function, and clinical outcomes were evaluated after phototherapy. Phototherapy significantly changed the composition of the skin microbiome of dogs with atopic dermatitis and significantly increased the relative abundance of the phyla Actinobacteria and Cyanobacteria. It significantly alleviated the clinical signs of canine atopic dermatitis without serious adverse effects. Transepidermal water loss, as a measure of skin barrier function, significantly decreased after phototherapy. In addition, phototherapy increased microbial diversity and decreased the relative abundance of Staphylococcus pseudintermedius associated with the severity of canine atopic dermatitis. These results suggest that the excimer light therapy is a suitable and safe therapeutic option for canine atopic dermatitis, which is also a spontaneous animal model of atopic dermatitis.
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Search related cases →Original publication on Crossref: https://doi.org/10.3389/fvets.2021.762961