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Peer-reviewed veterinary case report

Amazonian plant extract helps heal dog wounds better than ointment

By Américo, Ádria Vanessa Linhares Dos Santos et al.·Published in Frontiers in veterinary science·2020·Federal University of Western Par&#xe1, Brazil·View original on PubMed

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Original publication title: Efficacy of Phytopharmaceuticals From the Amazonian Plantfor Wound Healing in Dogs.

Species:
dog

Plain-English summary

A group of 11 dogs with skin wounds was treated with two different herbal ointments made from the Amazonian plant Jucá, and their healing was compared to a standard commercial ointment. The dogs received treatment every other day for three weeks, and the results showed that both herbal ointments helped wounds heal better than the commercial option. The Jucá extracts not only promoted faster healing but also had antimicrobial properties, which means they could help prevent infections. This study suggests that Jucá could be a promising natural option for treating wounds in dogs.

People also search for: dog wound healing treatment · herbal ointment for dog wounds · Jucá extract for dogs

Abstract

We comparatively evaluate two distinct formulations containing 5% of Juc&#xe1; () for wound healing in dogs. An excision model study was performed in 11 dogs with three dermal wounds in each animal, which were treated with: (1) topical phytopharmaceutical based on Carbopol (PyC) containing 5% Juc&#xe1; ethanolic extract; (2) topical phytopharmaceutical based onbutter (PyM) containing 5% Juc&#xe1; ethanolic extract; and (3) commercial ointment (control). Wound treatment was carried out on alternated days starting at day (D) one until D21. Macroscopic (all time-points) and histological (D0 and D21) analyses were performed. The antimicrobial activity of Juc&#xe1; was evaluated through Minimal Inhibitory Concentration (MIC). Phytochemical analysis of Juc&#xe1; revealed 3.1% phenolic compound content expressed in rutin and the presence of hydrolyzable tannins and flavonoids. The mean wound retraction was 33.7 &#xb1; 5.5, 34.0 &#xb1; 4.7, and 28.4 &#xb1; 4.9 % for PyC, PyM, and control groups, respectively, with higher wound retraction for both herbal-treated groups compared to the control (< 0.05). Alcoholic extract of Juc&#xe1; had antimicrobial activity against the microorganisms, andat different degrees, with MIC ranging from 250 to 16.625 &#x3bc;g/ml. Microscopic evaluation showed that the phytotherapic formulations contributed to better dermal wound healing through wound fibroplasia. The alcoholic extract of Juc&#xe1; pods has great potential for wound healing in dogs and can be used in the development of commercially viable phytotherapic formulations.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32656247/