Peer-reviewed veterinary case report
Selamectin vs fipronil spot-on for killing adult cat fleas and eggs
By Dryden, Michael et al.·Published in Veterinary therapeutics : research in applied veterinary medicine·2007·Department of Diagnostic Medicine/Pathology, United States·View original on PubMed →
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Original publication title: Efficacy of selamectin and fipronil-(S)-methoprene spot-on formulations applied to cats against adult cat fleas (Ctenocephalides felis), flea eggs, and adult flea emergence.
- Species:
- cat
Plain-English summary
A group of cats infested with adult fleas was treated with either selamectin or fipronil-(S)-methoprene to see which worked better at getting rid of the fleas and their eggs. Selamectin was more effective at controlling adult fleas and reducing egg production in the first few weeks, while fipronil-(S)-methoprene showed better results in reducing flea emergence by the end of the study. Both treatments helped significantly with flea problems over the six weeks. Pet owners can feel reassured that these treatments can effectively manage flea infestations in cats.
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Abstract
A study was conducted to evaluate the efficacy of selamectin and fipronil-(S)-methoprene against adult cat fleas (Ctenocephalides felis), flea egg production, and the viability of flea eggs collected from treated cats. Cats were infested with approximately 50 adult fleas 2 days before treatment and weekly thereafter; flea eggs were collected and counted on days 0, 1, 2, and 3 and 48 and 72 hours after each weekly flea infestation. Live fleas were collected approximately 72 hours after treatment or infestation. Compared with fipronil-(S)-methoprene, selamectin provided significantly greater control of adult fleas from days 24 to 31 and significantly greater reduction in egg production from days 16 to 45. For the most part, both products significantly impacted larval and adult emergence for the entire 6-week study, with fipronil-(S)-methoprene providing significantly greater reduction in larval and adult emergence at week 6.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18183544/