Peer-reviewed veterinary case report
New topical terbinafine cream clears cat ringworm faster than
By Ivaskiene, M et al.·Published in Polish journal of veterinary sciences·2016·View original on PubMed →
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Original publication title: Efficacy of Topical Therapy with Newly Developed Terbinafine and Econazole Formulations in the Treatment of Dermatophytosis in Cats.
- Species:
- cat
Plain-English summary
A group of 40 cats with a common skin infection called dermatophytosis, caused by a fungus, were treated with either terbinafine cream or econazole cream. Cats treated with terbinafine recovered in about 20 days, while those on econazole took around 28 days to heal. Some cats using the econazole cream experienced skin redness and irritation. Overall, terbinafine was found to be more effective for treating this condition in cats.
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Abstract
In the field of veterinary dermatology dermatophytosis is one of the most frequently occurring infectious diseases, therefore its treatment should be effective, convenient, safe and inexpensive. The aim of this study was to evaluate the efficacy of newly developed topical formulations in the treatment of cats with dermatophytosis. Evaluation of clinical efficacy and safety of terbinafine and econazole formulations administered topically twice a day was performed in 40 cats. Cats, suffering from the most widely spread Microsporum canis-induced dermatophytosis and treated with terbinafine hydrochloride 1% cream, recovered within 20.3±0.88 days; whereas when treated with econazole nitrate 1% cream, they recovered within 28.4±1.14 days. A positive therapeutic effect was yielded by combined treatment with local application of creams and whole coat spray with enilconazole 0.2% emulsion "Imaverol". Most cats treated with econazole cream revealed redness and irritation of the skin at the site of application. This study demonstrates that terbinafine tended to have superior clinical efficacy (p<0.001) in the treatment of dermatophytosis in cats compared to the azole tested.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27760032/