Peer-reviewed veterinary case report
Effectiveness of two worm treatments for Toxocara in dogs
By Heredia Cardenas, Rafael et al.·Published in Veterinary parasitology·2017·Doctorado en Ciencias Agropecuarias y Recursos Naturales·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Efficacy of two anthelmintic treatments, spinosad/milbemycin oxime and ivermectin/praziquantel in dogs with natural Toxocara spp. infection.
- Species:
- dog
Plain-English summary
A group of 200 dogs diagnosed with a common parasite called Toxocara were treated with either spinosad/milbemycin oxime or ivermectin/praziquantel to see which worked better. After treatment, the dogs given spinosad/milbemycin oxime showed a significant reduction in Toxocara eggs in their stool, with an 87% decrease at two weeks and 94% at four weeks. In comparison, the ivermectin/praziquantel group had a 71% decrease at two weeks and 88% at four weeks. Overall, spinosad/milbemycin oxime was more effective in clearing the infection than ivermectin/praziquantel.
People also search for: dog Toxocara treatment · spinosad milbemycin for dogs · ivermectin praziquantel effectiveness
Abstract
Toxocara canis is one of the most important zoonotic parasites of dogs. The aim of the present study was to compare the efficacy of spinosad/milbemycin oxime and ivermectin/praziquantel in dogs naturally infected with Toxocara spp. We studied 200 dogs with a positive diagnosis of Toxocara spp. Through coproparasitoscopic analysis, two study groups of 100 dogs each were assigned: spinosad/milbemycin oxime at a dose of 30-60mg/kg and 0.75-1.0mg/kg, respectively, or ivermectin/praziquantel administered at a dose of 0.2mg/kg and 5mg/kg, respectively. Both groups received a single dose. Three stool samples, one at day 0 before treatment, and at 14 and 28days post-treatment were examined using concentration-flotation techniques. In both treatments, the number of Toxocara spp. eggs decreased; with spinosad/milbemycin oxime treatment, eggs decreased by 87% at 14days (P=0.008) and 94% at 28days after treatment, compared with 71% at day 14 and 88% at day 28 in dogs medicated with ivermectin/praziquantel. The spinosad/milbemycin oxime treated group showed a greater decrease in the number of Toxocara spp. positive dogs compared to the group receiving ivermectin/praziquantel.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29080769/