Peer-reviewed veterinary case report
Tylosin tartrate effectiveness against dog Staphylococcus skin
By Scott, Brian A et al.·Published in Veterinary therapeutics : research in applied veterinary medicine·2010·McKeever Dermatology Clinics, United States·View original on PubMed →
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Original publication title: Efficacy of tylosin tartrate on canine Staphylococcus intermedius isolates in vitro.
- Species:
- dog
Plain-English summary
A study found that a common skin infection in dogs, caused by a bacteria called Staphylococcus intermedius, is becoming harder to treat due to antibiotic resistance. Researchers tested a lesser-known antibiotic called tylosin tartrate on samples from dogs with untreated skin infections and found that most of the bacteria were still sensitive to it. This suggests that tylosin tartrate could be a good option for treating these infections in dogs, especially when other antibiotics might not work. Further research is needed to confirm its effectiveness as a first-line treatment.
People also search for: dog skin infection treatment · tylosin for dog pyoderma · antibiotic resistance in dogs
Abstract
In the past 5 years, the incidence of canine skin infections caused by resistant strains of Staphylococcus (pseud)intermedius has increased. Many older antibiotics are used to treat these infections because the sensitivity can be demonstrated in vitro. Additionally, many of these older drugs are efficacious and unlikely to induce multidrug resistance. More than a decade ago, the antibiotic tylosin tartrate was reported to be efficacious in vitro and in vivo against Staphylococcus intermedius. The purpose of this study was to determine whether S. (pseud)intermedius isolated from untreated pyoderma cases at veterinary referral centers across the United States are sensitive in vitro to this antibiotic. Minimum inhibitory concentrations for tylosin tartrate and other commonly used antibiotics were determined for 103 isolates. Most (82.61%) of the isolates not exposed to antibiotics in the 3 months before submission were sensitive to tylosin tartrate. These findings suggest that tylosin tartrate warrants further study as a first-line option for the treatment of dogs initially presenting with pyoderma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20960412/