Peer-reviewed veterinary case report
Dog developed electrolyte problems and heart arrhythmias after cancer
By Kadar, Elissa et al.·Published in Journal of the American Animal Hospital Association·2004·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Electrolyte disturbances and cardiac arrhythmias in a dog following pamidronate, calcitonin, and furosemide administration for hypercalcemia of malignancy.
- Species:
- dog
Plain-English summary
A 13-year-old dog was diagnosed with high calcium levels due to cancer in the anal sacs. To treat this, the vet used a combination of fluids, medications, and surgery. After receiving pamidronate, the dog developed low magnesium levels, which may have led to heart rhythm problems during anesthesia. The vet was able to manage the situation, but it highlights the importance of monitoring electrolyte levels in dogs receiving this treatment.
People also search for: dog high calcium treatment · pamidronate side effects in dogs · dog heart problems after surgery
Abstract
A 13-year-old dog was diagnosed with hypercalcemia of malignancy associated with adenocarcinoma of the anal sacs. Hypercalcemia was treated with intravenous (IV) 0.9% sodium chloride (NaCl), furosemide, calcitonin, and pamidronate. Hypomagnesemia was documented by 72 hours following a single, IV dose of pamidronate. The dog subsequently underwent surgery to remove the primary tumors, and multiple cardiac arrhythmias occurred during anesthesia. This case documents electrolyte abnormalities in a dog following treatment with pamidronate in conjunction with other therapies used to manage hypercalcemia. The authors postulate that hypomagnesemia may have contributed to the arrhythmias that occurred during anesthesia. Electrolyte abnormalities should be anticipated and corrected following pamidronate therapy in canine patients.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14736909/