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Peer-reviewed veterinary case report

Elevated synovial fluid concentration of adenosine triphosphate in dogs with osteoarthritis or sodium urate-induced synovitis of the stifle.

Journal:
Veterinary and comparative orthopaedics and traumatology : V.C.O.T
Year:
2016
Authors:
Torres, Bryan T et al.
Affiliation:
University of Missouri · United States
Species:
dog

Abstract

Adenosine triphosphate has been shown to stimulate nociceptive nerve terminals in joints. Elevated synovial fluid adenosine triphosphate concentrations as well as a correlation between synovial fluid adenosine triphosphate concentrations and osteoarthritic knee pain has been demonstrated in humans, but not yet in dogs. This study documented elevated synovial fluid adenosine triphosphate concentrations in the stifles of dogs with secondary osteoarthritis and urate-induced synovitis, as compared to normal stifles.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/27432274/