Peer-reviewed veterinary case report
Serum surfactant protein-A rises with worsening eosinophilic
By Sone, Katsuhito et al.·Published in The Journal of veterinary medical science·2016·Department of Veterinary Clinical Sciences, Japan·View original on PubMed →
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Original publication title: Elevation of serum surfactant protein-A with exacerbation in canine eosinophilic pneumonia.
- Species:
- dog
Plain-English summary
A 7-year-old female spayed Labrador Retriever was brought to the vet because she had a persistent cough with mucus. After tests, she was diagnosed with canine eosinophilic pneumonia, a condition where the lungs become inflamed due to a high number of eosinophils (a type of white blood cell). The vet started her on steroid treatment, which worked well, and her cough went away. The study also found that a specific protein in her blood, surfactant protein-A, increased when her symptoms worsened and decreased as she improved, suggesting it could be a helpful marker for this condition.
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Abstract
A 7-year-old female spayed Labrador Retriever was admitted to our hospital, because of cough with sputum. She was diagnosed as having canine eosinophilic pneumonia (CEP) based on blood eosinophilia, bronchial pattern and infiltrative shadow observed on thoracic radiography, bronchiolar obstruction and air-space consolidation predominantly affecting the right caudal lung lobe, as revealed by computed tomography (CT), predominant eosinophils in CT-guided fine needle aspiration and the clinical course. She exhibited a good response to steroid therapy, and the cough disappeared. The serum surfactant protein (SP)-A level increased with the aggravated symptom and decreased markedly with improvement compared with the C-reactive protein level and the number of eosinophils. We propose that serum SP-A level is a good biomarker in CEP.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26300438/