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Peer-reviewed veterinary case report

Elezanumab Accelerates Post-Injury Regeneration of Olfactory Sensory Neurons in a Methimazole-Induced Mouse Model.

Journal:
International forum of allergy & rhinology
Year:
2025
Authors:
Mori, Eri et al.
Affiliation:
Department of Otorhinolaryngology · Japan

Abstract

Elezanumab accelerates olfactory sensory neuron regeneration in a methimazole-induced mouse model. Repulsive guidance molecule A blockade increases GAP43and OMPcells dorsally while sparing basal cells. This approach offers a novel therapy for sensorineural olfactory disorder.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/40879266/