Peer-reviewed veterinary case report
Embracing the heterogeneity of natural viruses in mouse studies.
- Journal:
- The Journal of general virology
- Year:
- 2022
- Authors:
- Fiege, Jessica K & Langlois, Ryan A
- Affiliation:
- Department of Microbiology and Immunology and the Center for Immunology · United States
Abstract
Animal models are a critical tool in modern biology. To increase reproducibility and to reduce confounding variables modern animal models exclude many microbes, including key natural commensals and pathogens. Here we discuss recent strategies to incorporate a natural microbiota to laboratory mouse models and the impacts the microbiota has on immune responses, with a focus on viruses.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/35737518/