Peer-reviewed veterinary case report
Emergence of amantadine-resistant H3N2 avian influenza A virus in South Korea.
- Journal:
- Journal of clinical microbiology
- Year:
- 2008
- Authors:
- Lee, Jiyeon et al.
- Affiliation:
- College of Medicine and Medical Research Institute · South Korea
- Species:
- bird
Abstract
We found a relatively high frequency of unique amantadine-resistant H3N2 and H9N2 avian influenza viruses (Val27Ile on M2 protein) isolated from live poultry markets in South Korea and confirmed that a Val27Ile single substitution in the M2 protein is enough to acquire the amantadine resistance phenotype by using reverse-genetically created human-avian reassortant viruses.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18845822/