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Peer-reviewed veterinary case report

Dog treated with corneal transplant for cloudy eye disease

By Armour, Micki D et al.·Published in Veterinary ophthalmology·2019·Armour Veterinary Ophthalmology, United States·View original on PubMed

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Original publication title: Endothelial keratoplasty for corneal endothelial dystrophy in a dog.

Species:
dog

Plain-English summary

A dog with corneal endothelial dystrophy (CED) was experiencing progressive swelling in the eye due to a buildup of fluid. To treat this, the veterinarian performed a specialized surgery called endothelial keratoplasty, which involved transplanting healthy tissue to replace the damaged area. After the surgery, the dog's cornea became clear within two weeks and remained healthy for a year after the procedure. The dog was comfortable both before and after the surgery, showing that this treatment can be effective for similar cases of CED.

People also search for: dog eye problems corneal dystrophy · endothelial keratoplasty for dogs · dog corneal swelling treatment

Abstract

OBJECTIVE: To assess the efficacy of an endothelial keratoplasty procedure at defined intervals to 1 year postoperatively for the treatment of corneal endothelial dystrophy (CED) in a canine patient. PROCEDURE: A dog diagnosed with CED with progressive corneal edema underwent an endothelial keratoplasty. The patient was examined pre- and postoperatively with slit lamp biomicroscopy and ultrasonic pachymetry. RESULTS: Mean central corneal thickness (CCT) measured with pachymetry was >1400 μm preoperatively and decreased postoperatively to 725 μm. The transplanted donor tissue became transparent 2 weeks postoperatively and incorporated with the recipient cornea. The graft remained transparent throughout the duration of the postoperative period evaluated in this study (2 weeks postoperatively to 1 year). The canine patient was comfortable pre- and postoperatively. CONCLUSIONS: Endothelial keratoplasty is a potential therapeutic option for canine cases with progressive corneal thickening due to CED. As this is a single case study, further investigation into the use of endothelial keratoplasty to treat CED is warranted. Moreover, canine patients with CED might serve as a surgical model for human patients with Fuchs' Endothelial Corneal Dystrophy.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30972947/