Peer-reviewed veterinary case report
Chitooligosaccharide diet boosts immunity and gut health in growing
By Cheng, Guoqiang et al.·Published in Frontiers in veterinary science·2023·Sichuan Academy of Chinese Medicine Sciences, China·View original on PubMed →
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Original publication title: Enhancing immune response, antioxidant capacity, and gut health in growing beagles through a chitooligosaccharide diet.
- Species:
- dog
Plain-English summary
A group of 12 male beagle puppies, around 6 weeks old, were given either a regular diet or a diet supplemented with chitooligosaccharides (COS) for 7 weeks to see how it affected their health. The puppies on the COS diet showed improved immune responses, with higher levels of antibodies against common dog viruses and increased antioxidant activity in their bodies. Additionally, the COS diet helped promote beneficial gut bacteria. Overall, the study suggests that adding COS to a puppy's diet could support their immune system and gut health.
People also search for: beagle puppy immune support · dog diet for gut health · chitooligosaccharides for dogs
Abstract
Chitooligosaccharides (COS) have attracted significant attention due to their unique biological activities, water solubility, and absorbable properties. The objective of the present study was to investigate the impact of COS-supplemented diets on the immune response, antioxidative capacity, hematology, serum biochemistry, and modulation of intestinal microbiota in growing beagles. Twelve weaning male beagles (6 weeks old; weighing 3.6 ± 0.6 kg) were fed either a control diet (food without COS, = 6) or a COS-supplemented diet ( = 6) twice daily for 7 weeks. Blood samples collected at weeks 4 and 7 indicated that hematology and serum biochemistry remained unaffected by COS supplementation. Compared with the control group, the test group showed higher levels of serum antibodies against the canine distemper virus and parvovirus, higher levels of immunoglobulin A, G, and M, and increased activities of superoxide dismutase, glutathione peroxidase, and catalase. In addition, COS was observed to modulate the intestinal flora by enhancing the presence of probiotics, such as,,,,, and. In summary, a COS-supplemented diet could effectively improve dog health by regulating immune function and antioxidant responses and modulating intestinal microbiota. This study highlights the potentiality of using COS as a valuable nutraceutical for growing dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38274661/