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Peer-reviewed veterinary case report

Enlightened Mannhemia haemolytica lung inflammation in bovinized mice.

Journal:
Veterinary research
Year:
2014
Authors:
Stellari, Fabio Franco et al.
Species:
rodent

Abstract

Polymorphonuclear cells diapedesis has an important contribution to the induced Mannhemia haemolytica (M. haemolytica) infection lung inflammation and IL-8 is the primary polymorphonuclear chemoattractant. Using a bovine IL-8/luciferase transiently transgenized mouse model, the orchestration among M. haemolytica, IL-8 promoter activation and neutrophilia was followed in real time by in vivo image analysis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/24460618/