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Peer-reviewed veterinary case report

Eosinophilic dermatitis with swelling in nine dogs compared to humans

By Holm, K S et al.·Published in Journal of the American Veterinary Medical Association·1999·Department of Clinical Studies, United States·View original on PubMed

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Original publication title: Eosinophilic dermatitis with edema in nine dogs, compared with eosinophilic cellulitis in humans.

Species:
dog

Plain-English summary

A group of nine dogs showed signs of a skin condition called eosinophilic dermatitis, which caused red, swollen patches on their skin. This condition is similar to a skin issue seen in humans and may be triggered by allergies to medications, insect bites, or other irritants. The exact cause is still unclear, but the dogs had a significant number of eosinophils, a type of white blood cell, in their skin. Treatment options may focus on managing the allergic reactions, but specific therapies were not detailed in the study.

People also search for: dog skin problems · eosinophilic dermatitis treatment · why is my dog’s skin red and swollen · dog allergies to insect bites

Abstract

A unique eosinophilic dermatitis with edema in dogs is characterized by extremely erythematous coalescing macules and plaques with associated edema, and is similar to eosinophilic cellulitis (Wells' syndrome) in humans. Histopathologic features include a profound eosinophilic dermal infiltrate, focal areas of collagen fiber degeneration surrounded by eosinophils (flame figures), dilated vessels, and dermal edema. Etiopathogenesis is unknown, but a hypersensitivity reaction to medications, arthropod bites, or other foreign antigens is suspected.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10476711/