Peer-reviewed veterinary case report
Kitten with chronic regurgitation diagnosed with eosinophilic
By Pera, Julie et al.·Published in Journal of the American Animal Hospital Association·2017·From the Hope Advanced Veterinary Center, United States·View original on PubMed →
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Original publication title: Eosinophilic Esophagitis in a Kitten.
- Species:
- cat
Plain-English summary
A 4-month-old male kitten was brought to the vet because he was regurgitating frequently and not gaining weight after switching to dry food. Tests showed that his esophagus was enlarged and had severe lesions, indicating a condition called eosinophilic esophagitis (EoE), which involves inflammation from certain white blood cells. The kitten improved significantly after switching to a special hydrolyzed diet, while adding steroids did not help further. Follow-up tests showed that the inflammation in his esophagus was nearly gone, confirming the effectiveness of the dietary change.
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Abstract
A 4 mo old intact male kitten was presented for chronic regurgitation and failure to thrive after weaning to dry food. Esophageal dilatation and severe diffuse proliferative lesions of the esophageal mucosa were found via radiography and esophagoscopy, respectively. Histopathologic examination revealed severe, chronic, diffuse, hyperplastic eosinophilic and mastocytic esophagitis. Eosinophilic infiltrates were prominent, with a mean of 29.8 eosinophils per high power field, supportive of eosinophilic esophagitis (EoE). Significant clinical improvement was seen with dietary modification using a hydrolyzed diet. The addition of glucocorticoids did not result in further improvement in clinical signs. Repeat histopathology showed near resolution of eosinophilic infiltration. EoE is an uncommon and rarely reported condition in dogs and cats. Diagnosis involves histopathologic confirmation and exclusion of other causes of eosinophilic infiltration within the esophagus. This case report demonstrates the importance of biopsy in identification of EoE and the efficacy of dietary modification in the treatment of this disease in a kitten.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28535136/