Peer-reviewed veterinary case report
Infection signs and features in dogs - a review
By El Hamiani Khatat, Sarah et al.·Published in Frontiers in veterinary science·2021·Department of Medicine·View original on PubMed →
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Original publication title: Epidemiological and Clinicopathological Features ofInfection in Dogs: A Systematic Review.
- Species:
- dog
Plain-English summary
A 5-year-old mixed-breed dog was brought to the vet showing signs of lethargy, loss of appetite, weight loss, and joint pain. The vet suspected a tick-borne infection called canine granulocytic anaplasmosis, which can cause these symptoms along with changes in blood tests. Treatment typically involves antibiotics, and many dogs respond well, often showing improvement within a few days. It's important for pet owners to be aware of tick prevention to help protect their dogs from these infections.
People also search for: dog lethargy and loss of appetite · tick-borne disease in dogs · canine granulocytic anaplasmosis treatment
Abstract
is a worldwide emerging zoonotic tick-borne pathogen transmitted byticks and naturally maintained in complex and incompletely assessed enzootic cycles. Several studies have demonstrated an extensive genetic variability with variable host tropisms and pathogenicity. However, the relationship between genetic diversity and modified pathogenicity is not yet understood. Because of their proximity to humans, dogs are potential sentinels for the transmission of vector-borne pathogens. Furthermore, the strong molecular similarity between human and canine isolates ofin Europe and the USA and the positive association in the distribution of human and canine cases in the USA emphasizes the epidemiological role of dogs.infects and survives within neutrophils by disregulating neutrophil functions and evading specific immune responses. Moreover, the complex interaction between the bacterium and the infected host immune system contribute to induce inflammatory injuries. Canine granulocytic anaplasmosis is an acute febrile illness characterized by lethargy, inappetence, weight loss and musculoskeletal pain. Hematological and biochemistry profile modifications associated with this disease are unspecific and include thrombocytopenia, anemia, morulae within neutrophils and increased liver enzymes activity. Coinfections with other tick-borne pathogens (TBPs) may occur, especially with, complicating the clinical presentation, diagnosis and response to treatment. Although clinical studies have been published in dogs, it remains unclear if several clinical signs and clinicopathological abnormalities can be related to this infection.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34250067/