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Peer-reviewed veterinary case report

Epidemiological pattern of classical Borna disease and regional genetic clustering of Borna disease viruses point towards the existence of to-date unknown endemic reservoir host populations.

Journal:
Microbes and infection
Year:
2006
Authors:
Dürrwald, Ralf et al.
Affiliation:
Impfstoffwerk Dessau-Tornau GmbH (IDT) · Germany

Abstract

Classical Borna disease (cBD), a non-purulent encephalitis of solipeds and sheep, is endemic in certain areas of central Europe. The etiologic agent is Borna disease virus (BDV), thus far the only member of the family Bornaviridae. Based on epidemiological patterns of cBD and recent phylogenetic findings this review hypothesizes the possible existence of yet unknown BDV reservoir host populations, and analyzes critically BDVs from outside endemic regions.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16469519/