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Peer-reviewed veterinary case report

How mast cell tumour grades affect different dog breeds and ages

By Śmiech, Anna et al.·Published in Polish journal of veterinary sciences·2017·.·View original on PubMed

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Original publication title: Epidemiological Study of Canine Mast Cell Tumours According to the Histological Malignancy Grade.

Species:
dog

Plain-English summary

A study found that certain dog breeds are more likely to develop mast cell tumors, which are a type of skin tumor. Boxers, Labrador Retrievers, American Staffordshire Terriers, and Golden Retrievers had the highest rates of these tumors. Older dogs, especially those aged 11-16, were more likely to have more serious tumors, while younger dogs aged 2-6 were more prone to less severe types. The location of the tumor also varied by breed, with French Bulldogs often having tumors on the head and neck, while Boxers were more likely to have them in the scrotal area. Understanding these patterns can help pet owners and veterinarians monitor for signs of mast cell tumors in at-risk breeds.

People also search for: dog skin tumor breeds · mast cell tumor symptoms in dogs · Boxer mast cell tumor treatment

Abstract

The aim of the study was to identify significant relationships between the tumour malignancy grade and dogs' age, breed, sex, size, and location of mast cell tumours (MCTs). MCTs accounted for 13.27% of all diagnosed canine skin tumours. The highest incidence was recorded among Boxers, Labrador Retrievers, American Staffordshire Terriers, and Golden Retrievers. Statistical analysis revealed significantly higher probability of occurrence of the grade I mast cell tumour in the French Bulldog in the head, neck, torso, and limb regions, the grade-II mast cell tumour in Boxer, Doberman, Dachshund, shepherds, and setters in the scrotal region, and the grade III mast cell tumour in Shar-Pei in the axilla region. In the group of the oldest dogs aged 11-16, there was higher risk of development of MCTs grade II and III. Young dogs (aged 2-3 and 4-6) were found to be more prone to development of MCTs grade I. There was no correlation between MCTs grade and dogs' sex and size. To the authors' knowledge this is the first report on statistical relationships between the degree of mast cell tumour malignancy and dogs' phenotypic traits, age and tumour location. This analysis indicate predilections for development of the particular mast cell tumour malignancy degrees in certain dog breeds, age, and anatomical location.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29166281/