Peer-reviewed veterinary case report
Canine Wei Syndrome causing hind limb paralysis and blood flow changes
By Shuo Yang et al.·Published in Animals·2024·College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China, CH·View original on DOAJ →
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Original publication title: Epidemiology of Canine <i>Wei Syndrome</i> and Its Hemorheology Characteristics
- Species:
- dog
Plain-English summary
A 4-year-old male Poodle was diagnosed with Wei Syndrome, a condition that caused him to lose the ability to move his hind legs and resulted in muscle wasting. This syndrome is more common in male dogs, especially Poodles, and tends to occur more frequently during the winter months. Treatment for Wei Syndrome can be challenging, but understanding its characteristics, including abnormal blood flow properties, can help veterinarians provide better care. While the study highlighted the need for tailored treatment approaches, specific recovery outcomes were not detailed.
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Abstract
Canine paraplegia is a common condition in small animal medicine, referred to as <i>Wei Syndrome</i> (<i>WS</i>) in Traditional Chinese Veterinary Medicine (TCVM). Common clinical manifestations encompass hind limb paralysis, motor dysfunction, muscle atrophy, and the absence of pain perception. <i>WS</i> is considered a difficult-to-treat disease in small animal practice. The objective of this study was to investigate the epidemiology of canine <i>WS</i> and the characteristics of hemorheology. A total of 53 dogs with <i>WS</i> and 53 healthy dogs were included in this study. A retrospective case-controlled study design was employed. Data regarding the gender, season of <i>WS</i> occurrence, breed, and age of dogs with <i>WS</i>, as well as hemorheology from dogs with <i>WS</i> and healthy dogs, were collected and analyzed using SPSS 27.0. The study findings revealed that male dogs were more susceptible to <i>WS</i> (77.36%, 41/53). <i>WS</i> cases occurred more frequently in Winter (33.96%, 18/53), and were commonly found in Poodle breeds (43.40%, 23/53). The most affected age of <i>WS</i> was between 3 and 6 years old (54.72%, 29/53). Except for plasma viscosity and fibrinogen, the hemorheology indices of canine <i>WS</i> were significantly higher than those of healthy dogs (<i>p</i> < 0.05), especially in male dogs, Poodles and Bulldogs, those between 3 to 10 years, and in Autumn and Winter. This study provides evidence that male Poodles and Bulldogs aged 3 to 6 years are more prone to developing <i>WS</i>, with Winter being the season of high disease incidence. Abnormal hemorheology is a characteristic feature in dogs with <i>WS</i>, which should be considered during the treatment of <i>WS</i>.
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Search related cases →Original publication on DOAJ: https://doi.org/10.3390/ani14182658