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Peer-reviewed veterinary case report

Epididymal mitochondrial status of hypothyroid rats examined by transmission electron microscopy.

Journal:
Biotechnic & histochemistry : official publication of the Biological Stain Commission
Year:
2013
Authors:
Palaoro, L A et al.
Affiliation:
Clinical Biochemistry Department
Species:
rodent

Abstract

Hypothyroid rats show alterations in the mobility of sperm recovered from their epididymides. The AgNOR technique, immunohistochemistry and transmission electron microscopy were used to investigate changes in epithelial cells from epididymides of rats treated with (131)I. Counting of NORs did not permit detection of changes in the proliferative capacity of epididymides of hypothyroid animals. Transmission electron microscopy revealed changes in the mitochondria of hypothyroid rats that probably are associated with incipient apoptosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23210616/