Peer-reviewed veterinary case report
Brain tumor with epithelioid and spindle cells in a dog
By T. Yaman et al.·Published in Veterinární Medicína·2018·View original on DOAJ →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Epithelioid and spindle-cell haemangioendothelioma in the brain of a dog: a case report
- Species:
- dog
Plain-English summary
A 9.5-year-old male Belgian Malinois showed signs of fatigue, loss of appetite, and breathing problems before sadly passing away. A necropsy revealed a small tumor in the brain, specifically in the area that controls vital functions. This tumor was identified as a type of cancer called epithelioid and spindle-cell hemangioendothelioma, which originates from blood vessels. Unfortunately, despite the findings, there was no treatment mentioned, and the dog did not survive.
People also search for: dog fatigue and loss of appetite · Belgian Malinois breathing problems · dog brain tumor symptoms
Abstract
A 9.5-year-old male Belgian malinois dog died after showing clinical symptoms that included fatigue, anorexia and dyspnoea. Necropsy revealed macroscopic findings in the brain and other organs. A solitary, brown-red-coloured mass, approximately 0.5 cm thick and 1.5 × 2 cm in diameter, was detected on the right side of the medulla oblongata, pons and cerebellum. The cut surface showed no invasion of the brain parenchyma. Histologically, the neoplasm was characterised by proliferation of endothelial cells, which showed epithelioid and spindle cell features. Some tumour cells had intracytoplasmic lumen formations containing red blood cells. The nuclei of the tumour cells were large and vesicular. In immunohistochemical experiments the tumour cells stained positive for factor VIII-related antigen, CD31 and CD34. A description is provided of the features of this epithelioid and spindle-cell haemangioendothelioma (EHE) that originated from vessels of the meninges in the subarachnoid space.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on DOAJ: https://doi.org/10.17221/128/2017-VETMED