Peer-reviewed veterinary case report
Equine clinical cytogenetics: the past and future.
- Journal:
- Cytogenetic and genome research
- Year:
- 2008
- Authors:
- Lear, T L & Bailey, E
- Affiliation:
- Veterinary Science Department · United States
- Species:
- horse
Plain-English summary
This study looks at how scientists have used genetic testing to help horses, especially in understanding problems like birth defects, miscarriages, and infertility. Over time, improvements in technology have made it easier to spot specific issues with chromosomes, which are the structures that carry genes. Recently, new genomic tools have allowed for even more detailed analysis of these chromosome problems. The report discusses the history of these genetic studies in horses and suggests that future advancements in genetics could further improve our understanding and treatment of these issues. Overall, the findings highlight the ongoing importance of genetic research in helping horses stay healthy.
Abstract
Cytogenetic analyses of horses have benefited the horse industry by identifying chromosomal aberrations causing congenital abnormalities, embryonic loss and infertility. Technical advances in cytogenetics enabled the identification of chromosome specific aberrations. More recently, advances in genomic tools have been used to more precisely define chromosome abnormalities. In this report we review the history of equine clinical cytogenetics, identify historical landmarks for equine clinical cytogenetics, discuss how the current use of genomic tools has benefited this area, and how future genomics tools may enhance clinical cytogenetic studies in the horse.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18467824/