Peer-reviewed veterinary case report
Equine herpesvirus 2-associated granulomatous dermatitis in a horse.
- Journal:
- Veterinary pathology
- Year:
- 2006
- Authors:
- Sledge, D G et al.
- Affiliation:
- The University of Georgia · United States
- Species:
- horse
Plain-English summary
In this case, a horse was diagnosed with a recurring skin condition called granulomatous dermatitis, which means there were areas of inflammation and tissue damage in the skin. The problem was linked to a virus known as equine herpesvirus 2, which was found in the horse's skin cells. Tests showed that the virus was causing changes in the skin's deeper layers, leading to the formation of large cells and inflammation. This case adds to the understanding of possible causes of skin diseases in horses, particularly those related to viral infections. The treatment and outcome details were not provided, so we can't say how the horse responded to any treatment.
Abstract
Granulomatous dermatitis in horses has been linked to many etiologies, including various parasites, fungi, and bacteria. Idiopathic forms of granulomatous inflammation-producing diseases, some of which are localized to the skin, also have been reported in horses. Herein we describe a case of recurrent equine granulomatous skin disease characterized by intranuclear viral inclusions within macrophages and giant cells. The histologic changes were primarily noted in the deep dermis and included multifocal to coalescing areas of necrosis marked by histiocytic cell infiltration and presence of giant cells. Electron microscopic examination revealed intranuclear and intracytoplasmic viral particles consistent with herpesvirus. Sequence results of the polymerase chain reaction product were consistent with equine herpesvirus 2, adding another possible etiology to the list of differentials in cases of equine granulomatous skin disease.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16846998/