Peer-reviewed veterinary case report
Equine viral arteritis in newborn foals: clinical, pathological, serological, microbiological and immunohistochemical observations.
- Journal:
- Equine veterinary journal
- Year:
- 1997
- Authors:
- Del Piero, F et al.
- Affiliation:
- Department of Pathology · United States
- Species:
- horse
Plain-English summary
This study looked at two outbreaks of equine viral arteritis (a viral infection affecting horses) in newborn foals. In both outbreaks, the foals showed serious respiratory problems, along with fever and low white blood cell or platelet counts if they survived more than a day. The main issues found during examinations were in the lungs, with signs of pneumonia and inflammation of blood vessels. Some foals also had kidney damage. The researchers were able to confirm the virus's presence using specific tests.
Abstract
Clinical, pathological, immunohistochemical, serological and microbiological findings are described for 2 geographically and temporally distinct equine arteritis virus (EAV) epidemics in newborn foals. Outbreak A occurred at a commercial Standardbred breeding facility; Outbreak B began in a group of research animals. Clinical signs were severe and primarily referable to the respiratory tract. Fever and leucopenia and/or thrombocytopenia were observed in foals surviving for more than 24 h. The most common gross pathological findings were limited to the respiratory tract. Common histopathological findings included interstitial pneumonia, lymphocytic arteritis and periarteritis with fibrinoid necrosis of the tunica media. Renal tubular necrosis was noted in 2 foals. Immunoperoxidase histochemistry combined with virus isolation was diagnostic in all cases.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/9234009/