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Peer-reviewed veterinary case report

ESAT-6 peptide recognition by bovine CD8+ lymphocytes of naturally infected cows in herds from southern Italy.

Journal:
Clinical and vaccine immunology : CVI
Year:
2006
Authors:
Vitale, Fabrizio et al.
Affiliation:
Istituto Zooprofilattico Sperimentale della Sicilia

Abstract

The aim of this study was to define epitopes of Mycobacterium bovis from ESAT-6 (early secretory antigen of 6 kDa) recognized by CD8+ T lymphocytes from cows naturally infected with Mycobacterium bovis. We found that bovine CD8+ T cells recognized 10 out of 11 ESAT-6 peptides tested.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16603624/