Peer-reviewed veterinary case report
E coli from pyometra and cystitis in the same animal are very similar
By Moni, Camila Azevedo et al.·Published in Journal of applied microbiology·2024·Laborató, Brazil·View original on PubMed →
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Original publication title: Escherichia coli isolated from pyometra and cystitis in the same animal exhibit a wide phenotypic similarity.
Plain-English summary
A female dog was diagnosed with both pyometra (a serious infection of the uterus) and cystitis (bladder infection) caused by the same strain of E. coli bacteria. Researchers found that the bacteria from both infections were very similar in how they behaved and responded to treatments. This suggests that the infections might have originated from the same source. Understanding this connection could help veterinarians develop better prevention strategies for these common conditions in female dogs.
People also search for: dog pyometra symptoms · dog cystitis treatment · E. coli infection in dogs
Abstract
AIMS: Pyometra and cystitis caused by Escherichia coli are common diseases identified in canine or feline females. The origin of pyometra infection remains uncertain, and effective prevention strategies for this disease are still unknown. This study aimed to provide a phenotypic characterization, including antimicrobial resistance and virulence profiles, of endometrial pathogenic (EnPEC) and uropathogenic (UPEC) E. coli strains isolated simultaneously from the same animal. METHODS AND RESULTS: Sixteen E. coli strains, from eight different animals, were analyzed in this study. The antimicrobial susceptibility profile of EnPEC and UPEC strains was determined using the disc diffusion method, which showed a similar susceptibility profile among strains (EnPEC and UPEC) from the same animal. The virulence profile of the strains was assessed through biofilm formation, as well as serum resistance abilities. EnPEC and UPEC strains from the same animal exhibited slight variations in their virulence and antimicrobial resistance capabilities. Overall, most of the strain pairs showed a high similarity in their ability to establish biofilms and survive in serum complement activity. CONCLUSIONS: Overall, strains of E. coli isolated from both pyometra and cystitis in the same animal, despite presenting distinct clinical diseases, exhibit a wide phenotypic similarity, suggesting a common origin for the strains.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38692849/