Peer-reviewed veterinary case report
Establishment of a Zebrafish Infection Model for the Study of Wild-Type and Recombinant European Sheatfish Virus.
- Journal:
- Journal of virology
- Year:
- 2015
- Authors:
- Martín, Verónica et al.
- Affiliation:
- Centro de Investigació · Spain
- Species:
- reptile
Abstract
Amphibian-like ranaviruses include pathogens of fish, amphibians, and reptiles that have recently evolved from a fish-infecting ancestor. The molecular determinants of host range and virulence in this group are largely unknown, and currently fish infection models are lacking. We show that European sheatfish virus (ESV) can productively infect zebrafish, causing a lethal pathology, and describe a method for the generation of recombinant ESV, establishing a useful model for the study of fish ranavirus infections.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/26246565/