Peer-reviewed veterinary case report
Establishment of valnemulin susceptibility breakpoint against Clostridium perfringens in rabbits.
- Journal:
- Anaerobe
- Year:
- 2017
- Authors:
- Tao, Meng-Ting et al.
- Affiliation:
- South China Agricultural University · China
- Species:
- rabbit
Abstract
Susceptibility breakpoints provide fundamental information for rational administration of antibiotics. The present investigation reports the first valnemulin susceptibility breakpoint (MIC<0.25 μg/mL) against Clostridium perfringens infections in rabbits based on the wild-type cutoff (CO) and the pharmacokinetics/pharmacodynamic (PK/PD) cutoff (CO). The established susceptibility breakpoint of valnemulin might be useful in resistance surveillance of pleuromutilins and development of clinical breakpoints.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28801120/