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Peer-reviewed veterinary case report

Estimation of paracrine signaling using quantitative RT-PCR from multiple patchy lesion samples.

Journal:
Molecular and cellular probes
Year:
2013
Authors:
Jiao, Shuang et al.
Affiliation:
Niigata University Graduate School of Medical and Dental Sciences · Japan
Species:
rodent

Abstract

We investigated whether correlations between mRNA levels of cytokines versus other proteins from patchy lesion could estimate cytokine paracrine signaling in vivo. Experiments with rat experimental autoimmune myocarditis (EAM), a patchy myocarditis model, indicated IL-1 and other protein levels were correlated, indicating paracrine signaling pathways in vivo.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22921513/