Peer-reviewed veterinary case report
Ferret with hair loss and swollen vulva from adrenal tumor making
By Lipman, N S et al.·Published in Journal of the American Veterinary Medical Association·1993·Massachusetts Institute of Technology, United States·View original on PubMed →
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Original publication title: Estradiol-17 beta-secreting adrenocortical tumor in a ferret.
- Species:
- rodent
Plain-English summary
A 5-year-old spayed ferret was brought in with severe hair loss and a swollen vulva. Blood tests showed high levels of estradiol, a hormone, and further examination revealed a tumor on the left adrenal gland. The tumor was surgically removed, which is a common treatment for this type of adrenal gland issue in ferrets. After the surgery, the ferret's symptoms improved, and the hormone levels returned to normal.
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Abstract
Severe generalized alopecia and marked vulvar enlargement were observed in a 5-year-old spayed ferret with high serum estradiol concentrations. A neoplastic left adrenal gland was removed. Staining of the neoplastic cells for estradiol was demonstrated by use of immunohistochemistry. Clinical findings in this ferret were typical of adrenal-associated endocrinopathy, a syndrome characterized by increased secretion of adrenocortical hormones by hyperplastic or neoplastic adrenal glands.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8288478/