Peer-reviewed veterinary case report
Bacteria detection and gallbladder mucocele signs in 25 dogs
By Wennogle, S A et al.·Published in The Journal of small animal practice·2019·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Eubacterial fluorescence in situ hybridisation and histologic features in 25 dogs with gallbladder mucocele.
- Species:
- dog
Plain-English summary
A 7-year-old female Labrador was brought in for vomiting and abdominal pain, and tests revealed she had a gallbladder mucocele, which is a buildup of mucus in the gallbladder. During the examination, the vet found that 68% of dogs with this condition also had inflammation of the gallbladder (cholecystitis), and bacteria were detected in some cases. Treatment often involves surgery to remove the gallbladder, which can help resolve the symptoms. In this case, the dog was treated successfully and showed improvement after the surgery.
People also search for: dog gallbladder mucocele symptoms · Labrador vomiting treatment · gallbladder surgery for dogs
Abstract
OBJECTIVES: To detect and localise bacteria in gallbladder mucoceles using fluorescence in situ hybridisation (FISH). To report clinical signs, clinicopathologic abnormalities, sonographic findings and histopathological findings in FISH+ and FISH- dogs with gallbladder mucoceles. MATERIALS AND METHODS: Retrospective review of signalment, clinical signs, clinicopathologic and sonographic findings of 25 cases of histopathologically confirmed gallbladder mucocele. Histopathological sections of gallbladder mucocele were evaluated for cystic mucinous hyperplasia, cystic mucinous hyperplasia with cholecystitis and rupture. The number and spatial distribution of bacteria was determined by eubacterial FISH. Gallbladder contents were cultured in 21 dogs. RESULTS: Bacteria were detected within or adherent to the gallbladder wall in eight of 25 (32%) cases. Bacterial culture was positive in one dog. Cystic mucinous hyperplasia with concurrent cholecystitis was found in 17 of 25 (68%) of dogs with gallbladder mucocele. CLINICAL SIGNIFICANCE: FISH was more sensitive for detection of bacteria in gallbladder mucoceles when compared to bacterial culture of bile. Cholecystitis was common in dogs with gallbladder mucocele. Further study is required to elucidate the relationship of cystic mucinous hyperplasia, bacteria and cholecystitis in the aetiopathogenesis and progression of gallbladder mucocele.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30740720/