Peer-reviewed veterinary case report
Gelatin matrix stops liver bleeding in dogs after biopsy
By Polidoro, Daniel P & Kass, Philip H·Published in Journal of the American Animal Hospital Association·2013·Department of Surgery, United States·View original on PubMed →
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Original publication title: Evaluation of a gelatin matrix as a topical hemostatic agent for hepatic bleeding in the dog.
- Species:
- dog
Plain-English summary
A group of 14 dogs underwent liver biopsies and experienced bleeding at the biopsy sites. To stop the bleeding, one site was treated with a new gelatin matrix containing thrombin, while the other was treated with a standard gelatin sponge. The results showed that the gelatin matrix worked faster and resulted in less blood loss compared to the sponge, with no adverse reactions noted in the first 24 hours after surgery. This new treatment option appears to be a safe and effective way to manage bleeding during liver procedures in dogs.
People also search for: dog liver biopsy bleeding treatment · gelatin matrix for dog surgery · how to stop dog bleeding after surgery
Abstract
New generation topical hemostatic agents containing thrombin have been developed for use in surgical procedures when control of bleeding by conventional methods is either ineffective or impractical. The authors compared the safety, hemostatic efficacy, and handling characteristics of a thrombin-containing topical surgical hemostatic agent (a gelatin matrix) to a hemostatic gelatin sponge for treatment of parenchymal bleeding after liver biopsy. Fourteen dogs were enrolled in this prospective clinical study. Paired 1.5 cm × 1.5 cm and 0.5 cm deep liver biopsies were obtained via laparotomy for each dog. One bleeding liver biopsy lesion was treated with the gelatin matrix and the other with a gelatin sponge. The treated liver biopsy sites were compared for bleeding severity, time to hemostasis, cumulative blood loss, and hemostatic agent handling characteristics. Median time to hemostasis was significantly shorter (P = 0.034) and median cumulative blood loss was significantly lower (P = 0.033) for the lesions treated with the gelatin matrix than the gelatin sponge. Adverse reactions were not observed within the first 24 hr postoperatively. When used to control parenchymal bleeding from liver biopsy sites in the dog, the evaluated gelatin matrix was safe and more effective than the gelatin sponge.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23861265/