Peer-reviewed veterinary case report
Surgical removal of dog skin mast cell tumors and outcomes using
By Saunders, Harvey et al.·Published in Veterinary and comparative oncology·2021·Department of Oncology, Australia·View original on PubMed →
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Original publication title: Evaluation of a modified proportional margin approach for complete surgical excision of canine cutaneous mast cell tumours and its association with clinical outcome.
- Species:
- dog
Plain-English summary
A study looked at 100 dogs with skin tumors called mast cell tumors (MCTs) to see how well a specific surgical technique worked for removing them. This method involved taking a 2 cm margin around larger tumors to ensure complete removal. The results were promising, with 95 out of 100 tumors completely excised and a low recurrence rate of only 3%. Most dogs did well after surgery, with only a small percentage developing new tumors or experiencing metastasis. This technique appears to be effective for treating MCTs in dogs.
People also search for: dog skin tumor treatment · mast cell tumor surgery in dogs · canine mast cell tumor recurrence rate
Abstract
Canine cutaneous mast cell tumours (MCTs) represent a common neoplasm in veterinary practice. Several reported techniques are available to guide surgical excision. Our study examined one hundred cutaneous MCTs that were excised surgically using a modified proportional margin approach. A 2 cm lateral margin upper limit was applied for any tumour diameter that exceeded this size with a deep surgical margin of one fascial plane applied. A retrospective, cross-sectional study with follow-up was used to determine the clinical utility of this excision technique. Associations between explanatory variables of tumour size and grade were compared with outcomes of complete excision and size of histologic tumour-free margins (HTFM) using the appropriate Pearson's χand Fisher's exact tests. Follow-up data evaluated tumour recurrence and patient survival. Ninety-five percent of MCTs (95/100) were completely excised. No significant association in the achievement of complete excision between low- and high-grade MCTs (P = .48) was noted. Tumour size was not associated with the rate of complete excision (P = .06). Tumour grade and size did not influence the size of the HTFM (P = .94 and P = .14, respectively). Overall, a recurrence rate of 3% (3/100 tumours) and de novo MCT development rate of 7.7% (5/65 dogs) was noted, with median follow-up period of 593 days (range 180-1460 days). Post-operative metastases were seen in 4.6% of dogs (3/65). Therefore, a modified proportional margin approach with 2 cm lateral margin upper limit is a suitable technique to guide surgical excision of canine cutaneous MCTs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32558125/