Peer-reviewed veterinary case report
Antibiotic use in dogs with suspected urinary tract infections
By Weese, Jeffrey Scott et al.·Published in Journal of veterinary internal medicine·2021·Ontario Veterinary College, Canada·View original on PubMed →
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Original publication title: Evaluation of antimicrobial prescriptions in dogs with suspected bacterial urinary tract disease.
- Species:
- dog
Plain-English summary
A study looked at dogs with urinary tract infections (UTIs) and how veterinarians prescribed antibiotics to treat them. The most common antibiotics used were amoxicillin/clavulanic acid, cefpodoxime, and amoxicillin, with treatment durations typically around 12 to 14 days. For dogs with recurrent UTIs, the same antibiotics were often prescribed, and some received combinations of drugs. The findings suggest that vets are increasingly using recommended first-line antibiotics and reducing treatment durations, which is a positive trend for managing UTIs in dogs.
People also search for: dog urinary tract infection treatment · antibiotics for dog UTI · recurrent cystitis in dogs
Abstract
BACKGROUND: Antimicrobials are commonly used to treat urinary tract disease in dogs. Understanding antimicrobial use is a critical component of antimicrobial stewardship efforts. HYPOTHESIS/OBJECTIVES: To evaluate antimicrobial prescriptions for dogs diagnosed with acute cystitis, recurrent cystitis, and pyelonephritis. ANIMALS: Dogs prescribed antimicrobials for urinary tract disease at veterinary practices in the United States and Canada. MATERIALS AND METHODS: A retrospective review of antimicrobial prescriptions was performed. RESULTS: The main clinical concerns were sporadic bacterial cystitis (n = 6582), recurrent cystitis (n = 428), and pyelonephritis (n = 326). Amoxicillin/clavulanic acid (2702, 41%), cefpodoxime (1024, 16%), and amoxicillin (874, 13%) were most commonly prescribed for sporadic bacterial cystitis. The median prescribed duration was 12 days (range, 3-60 days; interquartile range [IQR], 4 days). Shorter durations were used in 2018 (median, 10 days; IQR, 4 days) compared to both 2016 and 2017 (both median, 14 days; IQR, 4 days; P ≤ .0002). Amoxicillin/clavulanic acid (146, 33%), marbofloxacin (95, 21%), and cefpodoxime (65, 14%) were most commonly used for recurrent cystitis; median duration of 14 days (range, 3-77 days; IQR, 10.5 days). Amoxicillin/clavulanic acid (86, 26%), marbofloxacin (56, 17%), and enrofloxacin (36, 11%) were most commonly prescribed for pyelonephritis; however, 93 (29%) dogs received drug combinations. The median duration of treatment was 14 days (range, 3-77 days; IQR, 11 days). CONCLUSIONS AND CLINICAL IMPORTANCE: Decreases in duration and increased use of recommended first-line antimicrobials were encouraging. Common drug choices and durations should still be targets for antimicrobial stewardship programs that aim to optimize antimicrobial use, concurrently maximizing patient benefits while minimizing antimicrobial use and use of higher tier antimicrobials.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34397135/