Peer-reviewed veterinary case report
Azathioprine treatment results for dogs with perianal fistulas
By Harkin, Kenneth R et al.·Published in Journal of the American Animal Hospital Association·2007·Department of Clinical Sciences, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Evaluation of azathioprine on lesion severity and lymphocyte blastogenesis in dogs with perianal fistulas.
- Species:
- dog
Plain-English summary
Fourteen dogs with perianal fistulas, which are painful sores around the rear end, were treated with a medication called azathioprine to see if it could help. After treatment, eight dogs (about 57%) showed complete healing of their sores, one dog had partial improvement, while five dogs did not respond at all. Interestingly, the tests measuring immune response did not predict how well the dogs would do with the treatment. Overall, azathioprine helped some dogs recover from their painful condition.
People also search for: dog perianal fistula treatment · azathioprine for dogs · why does my dog have sores near his rear end
Abstract
Fourteen dogs with perianal fistulas were entered into a prospective clinical study to investigate the effects of long-term azathioprine on clinical outcome and to determine if the clinical results correlated with lymphocyte blastogenesis tests. Complete remission of perianal fistulas was seen in eight (57%) of 14 dogs; partial remission occurred in one (7%) dog; and no response was detected in five (36%) dogs. The results of lymphocyte blastogenesis assays did not correlate with therapeutic response.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17209081/