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Peer-reviewed veterinary case report

Evaluation of azathioprine on lesion severity and lymphocyte blastogenesis in dogs with perianal fistulas.

Journal:
Journal of the American Animal Hospital Association
Year:
2007
Authors:
Harkin, Kenneth R et al.
Affiliation:
Department of Clinical Sciences · United States
Species:
dog

Abstract

Fourteen dogs with perianal fistulas were entered into a prospective clinical study to investigate the effects of long-term azathioprine on clinical outcome and to determine if the clinical results correlated with lymphocyte blastogenesis tests. Complete remission of perianal fistulas was seen in eight (57%) of 14 dogs; partial remission occurred in one (7%) dog; and no response was detected in five (36%) dogs. The results of lymphocyte blastogenesis assays did not correlate with therapeutic response.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17209081/