Peer-reviewed veterinary case report
Calcium and blood changes in dogs with open and closed cervix pyometra
By Kurban, I et al.·Published in Polish journal of veterinary sciences·2024·stanbul University-Cerrahpaş·View original on PubMed →
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Original publication title: Evaluation of calcium, phosphorus and some biochemical parameters in dogs with open and closed cervix pyometra.
- Species:
- dog
Plain-English summary
A group of female dogs aged 5 to 10 years was studied to understand the effects of pyometra, a serious infection of the uterus, on their health. Out of 62 dogs, 40 were diagnosed with pyometra, with some having an open cervix and others a closed cervix. Blood tests showed that dogs with closed-cervix pyometra had higher white blood cell counts and alkaline phosphatase levels, indicating infection and possible liver issues. Dogs with open-cervix pyometra had elevated calcium levels, while those with closed-cervix showed increased phosphorus levels, suggesting kidney problems. This information can help veterinarians better diagnose and treat dogs suffering from pyometra.
People also search for: dog pyometra symptoms · elevated calcium in dogs · closed cervix pyometra treatment
Abstract
The aim of this study was to evaluate the changes in calcium, phosphorus and some biochemical parameters in dogs with open and closed cervix pyometra, which was then compared with a control group. A total of 62 bitches of age group 5-10 years old irrespective of breed were enrolled into the study. Control group consisted of 22 bitches which were clinically healthy and in luteal phase of the estrus cycle. On clinical examination, pyometra was diagnosed in 40 bitches while 23 out of 40 bitches had open-cervix pyometra and 17 of 40 bitches had closed-cervix pyometra. Evaluation of haematological changes revealed that there was increased white blood cell (WBC), total protein (TP), globulin, alkaline phosphatase (ALKP) while decreased glucose (Glu), albumin (Alb) and albumin globulin ratio in pyometra cases (p<0.001). The highest WBC and ALKP levels were detected in closed-cervix pyometra group (p<0.001). Calcium (Ca+2) levels had significant rise in open-cervix pyometra cases (p<0.05) while phosphorus (Phos) levels had tendency to increase in closed-cervix pyometra cases (p=0.08). Also, Ca was directly correlated with Glu, Alb and TP while inversely correlated with WBC and blood urea nitrogen/creatinine (BUN/Crea). However, Phos was significantly associated with BUN and Crea (p<0.001; R=0.915 and R=0.860, respectively). As a result of this study, it was observed that the increased Ca levels in open-cervix cases and the elevated Phos levels in closed-cervix cases, were associated with the biochemical parameters related to hepatic and renal dysfunction in dogs with pyometra.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39736065/