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Peer-reviewed veterinary case report

Cardiac troponin I blood test predicts survival in emergency dogs

By Porter, Adam et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2016·Cummings School of Veterinary Medicine - Clinical Sciences, United States·View original on PubMed

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Original publication title: Evaluation of cardiac troponin I in dogs presenting to the emergency room using a point-of-care assay.

Species:
dog

Plain-English summary

A group of dogs brought to the emergency room were tested for cardiac troponin I (cTnI), a protein that can indicate heart problems. Out of 129 dogs, 88 had normal levels, while 41 had elevated levels, which suggested a higher risk of death. Dogs with elevated cTnI had eight times the risk of mortality compared to those with normal levels, and those with high levels had 17 times the risk. This test could help veterinarians assess the heart health of dogs in emergency situations quickly and effectively.

People also search for: dog heart problems emergency room · elevated cardiac troponin I in dogs · dog mortality risk heart test

Abstract

We used a point-of-care assay to evaluate cardiac troponin I (cTnI) in clinically normal dogs and a heterogeneous population of dogs presenting to the emergency room (ER) and to determine whether cTnI has prognostic capabilities in an ER population. Fourteen clinically normal dogs and 129 dogs presented to the ER were evaluated. Of the study group, 88 dogs had normal cTnI (< 0.1 ng/mL), 29 had elevated cTnI (0.1 to 1.0 ng/mL), and 12 had high cTnI (> 1.0 ng/mL). Dogs with elevated cTnI had 8 times the odds of mortality compared to dogs with normal cTnI [odds ratio (OR): 8.2, 95% confidence interval (CI): 3.0, 22.3]. Dogs with high cTnI had 17 times higher odds of mortality compared to dogs with normal cTnI (OR: 17.6, 95% CI: 4.4, 70.1). We conclude that cTnI shows promise as a prognostic indicator for dogs presenting to the ER and can be easily evaluated using a point-of-care assay.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27247465/