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Peer-reviewed veterinary case report

Mesotherapy treatment options for hip osteoarthritis in dogs

By Alves, João C et al.·Published in Journal of the American Veterinary Medical Association·2024·1Divis&#xe3·View original on PubMed

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Original publication title: Evaluation of different substance combinations in a multiple-session mesotherapy protocol for the management of osteoarthritis in dogs: a retrospective study.

Species:
dog

Plain-English summary

A group of 104 dogs with hip osteoarthritis, averaging 7.6 years old, received different combinations of treatments to help manage their pain. The most effective treatments included a mix of lidocaine, piroxicam, and thiocolchicoside, with even better results when combined with photobiomodulation therapy (a light-based treatment). Dogs treated with these combinations showed significant improvements in pain and mobility over time. The findings suggest that these treatments can provide longer-lasting relief for dogs suffering from hip osteoarthritis.

People also search for: dog hip osteoarthritis treatment · mesotherapy for dogs · photobiomodulation therapy for dogs

Abstract

OBJECTIVE: To describe the effect of different substance combinations administered through mesotherapy in dogs with hip osteoarthritis. ANIMALS: 104 dogs. METHODS: In this retrospective study, 4 groups (dogs treated with a combination of lidocaine, piroxicam, and thiocolchicoside [MG]; dogs treated with lidocaine, piroxicam, and Traumeel [TG]; dogs treated with lidocaine, piroxicam, and glucosamine [GG]; and dogs treated with the same combination as in MG combined with a photobiomodulation session [MPG]) were set. For all groups, the same treatment frequency was followed. Response to treatment was measured with the Canine Brief Pain Inventory (divided into pain interference score and pain severity score), Liverpool Osteoarthritis in Dogs (LOAD), and Canine Orthopedic Index (divided into function, gait, stiffness, and quality of life) before treatment and 15, 30, 60, 90, and 120 days after treatment. Cox proportional hazard regression analysis was used to investigate the influence of treatment, age, sex, body weight, breed, and Orthopedic Foundation for Animals score. RESULTS: Dogs had a mean age of 7.6 ± 3.1 years and body weight of 28.6 ± 5.5 kg. Hip osteoarthritis was classified as mild (4), moderate (70), or severe (30). Greater improvements were observed in MG and MPG. Kaplan-Meier estimators showed MG and MPG had longer periods with clinically significant results. Treatment was the covariable that contributed more frequently to the outcomes observed. CLINICAL RELEVANCE: The combination used in MG, particularly combined with photobiomodulation, produced longer-lasting clinically significant results.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38503053/