Peer-reviewed veterinary case report
Survival factors in untreated dogs with nasal cancer
By Rassnick, Kenneth M et al.·Published in Journal of the American Veterinary Medical Association·2006·Department of Clinical Sciences, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Evaluation of factors associated with survival in dogs with untreated nasal carcinomas: 139 cases (1993-2003).
- Species:
- dog
Plain-English summary
A group of 139 dogs with untreated nasal tumors (carcinomas) was studied to understand their survival rates. The average survival time for these dogs was about 95 days, but those with nosebleeds (epistaxis) had a much shorter median survival of 88 days compared to 224 days for those without nosebleeds. This suggests that dogs showing signs of nosebleeds may have a worse prognosis. Overall, the findings indicate that untreated nasal carcinomas lead to a poor outcome, highlighting the need for better treatment options.
People also search for: dog nasal tumor survival · dog nosebleed prognosis · untreated nasal carcinoma in dogs
Abstract
OBJECTIVE: To evaluate factors associated with survival in dogs with nasal carcinomas that did not receive treatment or received only palliative treatment. DESIGN: Retrospective case series. ANIMALS: 139 dogs with histologically confirmed nasal carcinomas. PROCEDURES: Medical records, computed tomography images, and biopsy specimens of nasal carcinomas were reviewed. Only dogs that were not treated with radiation, surgery, chemotherapy, or immunotherapy and that survived > or = 7 days from the date of diagnosis were included. The Kaplan-Meier method was used to estimate survival time. Factors potentially associated with survival were compared by use of log-rank and Wilcoxon rank sum tests. Multivariable survival analysis was performed by use of the Cox proportional hazards regression model. RESULTS: Overall median survival time was 95 days (95% confidence interval [CI], 73 to 113 days; range, 7 to 1,114 days). In dogs with epistaxis, the hazard of dying was 2.3 times that of dogs that did not have epistaxis. Median survival time of 107 dogs with epistaxis was 88 days (95% CI, 65 to 106 days) and that of 32 dogs without epistaxis was 224 days (95% CI, 54 to 467 days). CONCLUSIONS AND CLINICAL RELEVANCE: The prognosis of dogs with untreated nasal carcinomas is poor. Treatment strategies to improve outcome should be pursued.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16881833/