Peer-reviewed veterinary case report
Blood test markers linked to parvovirus and inflammation in dogs
By Sevim, K et al.·Published in Topics in companion animal medicine·2025·Department of Internal Medicine·View original on PubMed →
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Original publication title: Evaluation of hematologic indices in parvovirus infected dogs with systemic inflammatory response syndrome (SIRS).
- Species:
- dog
Plain-English summary
A group of young dogs infected with parvovirus showed signs of severe illness, including vomiting and diarrhea, which can lead to a life-threatening condition called systemic inflammatory response syndrome (SIRS). Researchers looked at blood tests to see if certain indices could help diagnose and predict the outcome for these dogs. They found that specific blood markers were useful in diagnosing parvoviral enteritis and could also indicate how well the dogs might recover. This information can help veterinarians make better decisions when treating dogs with this serious infection.
People also search for: dog parvovirus symptoms · young dog vomiting diarrhea · parvovirus treatment for dogs
Abstract
Canine parvoviral enteritis (CPE) is a highly contagious, acute viral disease that mainly affects young dogs and can lead to systemic inflammatory response syndrome (SIRS), sepsis, endotoxemia and even death. The study aimed to evaluate the diagnostic and prognostic potential of hematological indices such as MLR, NLR, PLR, PNR and SII in CPV-infected dogs with SIRS at first admission. The retrospective study was performed on 51 CPV-infected and 20 healthy dogs. MLR, NLR, PLR, PNR, and SII indices were determined and compared between groups. A receiver operating characteristic (ROC) curve analysis was carried out to determine thresholds of sensitivity and specificity for hematologic indices. NLR, PLR, and PNR were the best predictors for supporting a diagnosis of parvoviral enteritis, with AUC values of 0.685, 0.762, and 0.884, respectively. Moreover, PLR and PNR, with AUC values of 0.740 and 0.769, respectively, were the most suitable indices to determine the prognosis of dogs with parvoviral enteritis with SIRS. In conclusion, these indices can be used as potential indicators for predicting disease outcomes and supporting a diagnosis of CPV-infected dogs with SIRS at first admission.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40086504/